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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: INPPL1 All Species: 24.85
Human Site: S1039 Identified Species: 54.67
UniProt: O15357 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15357 NP_001558.3 1258 138599 S1039 P R V G E G S S S D E E S G G
Chimpanzee Pan troglodytes XP_508622 1258 138671 S1039 P R V G E G S S S D E E S G G
Rhesus Macaque Macaca mulatta XP_001114794 1258 138636 S1039 P R V G E G S S S D E E S G G
Dog Lupus familis XP_542327 1264 138869 S1045 P R V G E G S S S D E E S G G
Cat Felis silvestris
Mouse Mus musculus Q6P549 1257 138955 S1040 P R V G E G S S S D E D S G G
Rat Rattus norvegicus Q9WVR3 1257 139124 S1040 P R V G E G S S S D E D S G G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517954 539 59681 E354 E F Y S T C L E E Y K K S Y E
Chicken Gallus gallus XP_426250 1017 112344 L832 I E F H S Y C L E E A Q R S G
Frog Xenopus laevis Q6P4S2 1019 115278 T834 F P F C T I L T H H G E E T G
Zebra Danio Brachydanio rerio Q2I6J1 1266 140353 I1036 S S E D D G N I G P H T G S L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789838 1327 148052 S1038 P M S A T P M S A T P M S A D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 98.4 96.3 N.A. 95.8 95.5 N.A. 31.7 42.9 39.3 65.8 N.A. N.A. N.A. N.A. 32.5
Protein Similarity: 100 99.6 98.7 97.3 N.A. 96.8 96.5 N.A. 35.4 55.4 53.3 75.9 N.A. N.A. N.A. N.A. 49.5
P-Site Identity: 100 100 100 100 N.A. 93.3 93.3 N.A. 6.6 6.6 13.3 6.6 N.A. N.A. N.A. N.A. 20
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 20 20 20 20 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 0 0 0 0 10 0 10 0 0 10 0 % A
% Cys: 0 0 0 10 0 10 10 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 10 10 0 0 0 0 55 0 19 0 0 10 % D
% Glu: 10 10 10 0 55 0 0 10 19 10 55 46 10 0 10 % E
% Phe: 10 10 19 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 55 0 64 0 0 10 0 10 0 10 55 73 % G
% His: 0 0 0 10 0 0 0 0 10 10 10 0 0 0 0 % H
% Ile: 10 0 0 0 0 10 0 10 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 10 10 0 0 0 % K
% Leu: 0 0 0 0 0 0 19 10 0 0 0 0 0 0 10 % L
% Met: 0 10 0 0 0 0 10 0 0 0 0 10 0 0 0 % M
% Asn: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % N
% Pro: 64 10 0 0 0 10 0 0 0 10 10 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % Q
% Arg: 0 55 0 0 0 0 0 0 0 0 0 0 10 0 0 % R
% Ser: 10 10 10 10 10 0 55 64 55 0 0 0 73 19 0 % S
% Thr: 0 0 0 0 28 0 0 10 0 10 0 10 0 10 0 % T
% Val: 0 0 55 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 10 0 0 10 0 0 0 10 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _